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Structure Report for: 4N8E

Name|DPP4 complexed with compound 12a
Revelation date|12-Feb-2014
Family|DPP4N_Peptidase_S9: there are 829 genes in this family, 179 structure(s)
Gene_locus|human-DPP4
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Ostermann, N., Zink, F., Kroemer, M.
Ligand|Inhibitor: CHEMBL3112966 Ligand in structure: Ligplot


Reference

    Title: Discovery of C-(1-aryl-cyclohexyl)-methylamines as selective, orally available inhibitors of dipeptidyl peptidase IV
    Namoto K, Sirockin F, Ostermann N, Gessier F, Flohr S, Sedrani R, Gerhartz B, Trappe J, Hassiepen U and Baeschlin DK <6 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 24:731, 2014 : PubMed

            



Representative scheme of DPP4N_Peptidase_S9 structure and an image from PDBsum server

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Databases

PDB-Sum4N8E Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP4N8E Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP4N8E Structural Classification Of Protein - SCOP server
PROTEOPEDIA4n8e 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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