4OCZ
Name : Crystal structure of human soluble epoxide hydrolase complexed with 1-(1-isobutyrylpiperidin-4-yl)-3-(4-(trifluoromethyl)phenyl)urea 1
Revelation date : 24-Sep-2014
Family : Epoxide_hydrolase
Gene_locus : human-EPHX2
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Lee, K.S.S., Liu, J., Wagner, K.M., Pakhomova, S., Dong, H., Morriseau, C., Fu, S.H., Yang, J., Wang, P., Ulu, A., Mate, C., Nguyen, L., Wullf, H., Eldin, M.L., Mara, A.A., Newcomer, M.E., Zeldin, D.C., Hammock, B.D.
Ligand :
References (1)
| Title : Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy - Lee_2014_J.Med.Chem_57_7016 |
| Author(s) : Lee KS , Liu JY , Wagner KM , Pakhomova S , Dong H , Morisseau C , Fu SH , Yang J , Wang P , Ulu A , Mate CA , Nguyen LV , Hwang SH , Edin ML , Mara AA , Wulff H , Newcomer ME , Zeldin DC , Hammock BD |
| Ref : Journal of Medicinal Chemistry , 57 :7016 , 2014 |
| Abstract : Lee_2014_J.Med.Chem_57_7016 |
| ESTHER : Lee_2014_J.Med.Chem_57_7016 |
| PubMedSearch : Lee_2014_J.Med.Chem_57_7016 |
| PubMedID: 25079952 |
| Gene_locus related to this paper: human-EPHX2 |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
