4W63

Name : Torpedo californica Acetylcholinesterase in complex with a tacrine-benzofuran hybrid inhibitor

Revelation date : 09-Sep-2015

Family : ACHE

Gene_locus : torca-ACHE

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Pesaresi, A., Samez, S., Lamba, D.

Ligand :

References (1)

Title : Novel Tacrine-Benzofuran Hybrids as Potent Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and X-ray Crystallography - Zha_2016_J.Med.Chem_59_114
Author(s) : Zha X , Lamba D , Zhang L , Lou Y , Xu C , Kang D , Chen L , Xu Y , De Simone A , Samez S , Pesaresi A , Stojan J , Lopez MG , Egea J , Andrisano V , Bartolini M
Ref : Journal of Medicinal Chemistry , 59 :114 , 2016
Abstract : Zha_2016_J.Med.Chem_59_114
ESTHER : Zha_2016_J.Med.Chem_59_114
PubMedSearch : Zha_2016_J.Med.Chem_59_114
PubMedID: 26632651
Gene_locus related to this paper: torca-ACHE

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

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