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Structure Report for: 4X6Y

Name|Human soluble epoxide hydrolase in complex with a cyclopropyl urea derivative
Revelation date|08-Apr-2015
Family|Epoxide_hydrolase: there are 1154 genes in this family, 155 structure(s)
Gene_locus|human-EPHX2
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Chiyo, N., Takai, K., Ishii, T.
Ligand|Inhibitor: CHEMBL3114611 Ligand in structure: Ligplot


Reference

    Title: Three-dimensional rational approach to the discovery of potent substituted cyclopropyl urea soluble epoxide hydrolase inhibitors
    Takai K, Chiyo N, Nakajima T, Nariai T, Ishikawa C, Nakatani S, Ikeno A, Yamamoto S, Sone T
    Ref: Bioorganic & Medicinal Chemistry Lett, 25:1705, 2015 : PubMed

            



Representative scheme of Epoxide_hydrolase structure and an image from PDBsum server

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Databases

PDB-Sum4X6Y Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP4X6Y Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP4X6Y Structural Classification Of Protein - SCOP server
PROTEOPEDIA4x6y 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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