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Structure Report for: 4Y2V

Name|Structure of soluble epoxide hydrolase in complex with (4-bromo-3-cyclopropyl-1H-pyrazol-1-yl)acetic acid
Revelation date|06-May-2015
Family|Epoxide_hydrolase: there are 1154 genes in this family, 155 structure(s)
Gene_locus|human-EPHX2
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Amano, Y., Yamaguchi, T.
Ligand|Inhibitor: CHEMBL3402239-4A5-4Y2V Ligand in structure: Ligplot


Reference

    Title: Identification of N-ethylmethylamine as a novel scaffold for inhibitors of soluble epoxide hydrolase by crystallographic fragment screening
    Amano Y, Tanabe E, Yamaguchi T
    Ref: Bioorganic & Medicinal Chemistry, :, 2015 : PubMed

            



Representative scheme of Epoxide_hydrolase structure and an image from PDBsum server

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Databases

PDB-Sum4Y2V Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP4Y2V Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP4Y2V Structural Classification Of Protein - SCOP server
PROTEOPEDIA4y2v 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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