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Structure Report for: 5FKJ

Name|Crystal structure of mouse acetylcholinesterase in complex with C-547, an alkyl ammonium derivative of 6-methyl uracil
Revelation date|16-Mar-2016
Family|ACHE: there are 538 genes in this family, 315 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Nachon, F., Villard-Wandhammer, M., Petrov, K., Masson, P
Ligand|Inhibitor: C-547 Ligand in structure: Ligplot


    Title: Slow-binding inhibition of acetylcholinesterase by an alkylammonium derivative of 6-methyluracil: mechanism and possible advantages for myasthenia gravis treatment
    Kharlamova AD, Lushchekina SV, Petrov KA, Kots ED, Nachon F, Villard-Wandhammer M, Zueva IV, Krejci E, Reznik VS and Masson P <2 more author(s)>
    Ref: Biochemical Journal, 473:1225, 2016 : PubMed


Representative scheme of ACHE structure and an image from PDBsum server


PDB-Sum5FKJ Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP5FKJ Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP5FKJ Structural Classification Of Protein - SCOP server
PROTEOPEDIA5fkj 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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