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Structure Report for: 5HF8

Name|Crystal structure of human acetylcholinesterase in complex with paraoxon (alternative acyl loop conformation)
Revelation date|22-Jun-2016
Family|ACHE: there are 538 genes in this family, 315 structure(s)
Gene_locus|human-ACHE
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Franklin, M.F., Rudolph, M.J., Ginter, C., Cassidy, M.S., Cheung, J
Ligand|Inhibitor: Paraoxon Ligand in structure: Ligplot


Reference

    Title: Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface
    Franklin MC, Rudolph MJ, Ginter C, Cassidy MS, Cheung J
    Ref: Proteins, 84:1246, 2016 : PubMed

            



Representative scheme of ACHE structure and an image from PDBsum server



Databases

PDB-Sum5HF8 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP5HF8 Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP5HF8 Structural Classification Of Protein - SCOP server
PROTEOPEDIA5hf8 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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