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Structure Report for: 5I8P

Name|Crystal structure of LP_PLA2 in complex with novel inhibitor
Revelation date|15-Jun-2016
Family|PAF-Acetylhydrolase: there are 149 genes in this family, 35 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Liu, Q.F., Chen, X.D., Chen, W.Y., Yuan, X.J., Su, H.X., Shen, J.H., Xu, Y.C.
Ligand|Inhibitor: CHEMBL3792924 Ligand in structure: Ligplot


    Title: Structural and Thermodynamic Characterization of Protein-Ligand Interactions Formed between Lipoprotein-Associated Phospholipase A2 and Inhibitors
    Liu Q, Chen X, Chen W, Yuan X, Su H, Shen J, Xu Y
    Ref: Journal of Medicinal Chemistry, 59:5115, 2016 : PubMed


Representative scheme of PAF-Acetylhydrolase structure and an image from PDBsum server


PDB-Sum5I8P Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP5I8P Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP5I8P Structural Classification Of Protein - SCOP server
PROTEOPEDIA5i8p 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

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