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Structure Report for: 5IKX

Name|Crystal structure of the alpha-esterase-7 carboxylesterase, E3, from Lucilia cuprina (supersedes 4FG5 06-Jun-2013)
Revelation date|22-Jun-2016
Family|Carb_B_Arthropoda: there are 1570 genes in this family, 32 structure(s)
Gene_locus|luccu-E3aest7
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Mutations : M364L, I419F, A472T, I505T, K530E, D554G authors Jackson, C.J., Liu,J-W., Carr, P.D., Younis, F., Pandey, G., Coppin, C., Meirelles, T., Ollis, D.L., Tawfik, D.S., Weik, M., Oakeshott, J.G.
Ligand|


Reference

    Title: Evolution of Protein Quaternary Structure in Response to Selective Pressure for Increased Thermostability
    Fraser NJ, Liu JW, Mabbitt PD, Correy GJ, Coppin CW, Lethier M, Perugini MA, Murphy JM, Oakeshott JG and Jackson CJ <1 more author(s)>
    Ref: Journal of Molecular Biology, 428:2359, 2016 : PubMed

            

    Title: Structure and function of an insect alpha-carboxylesterase (alphaEsterase7) associated with insecticide resistance
    Jackson CJ, Liu JW, Carr PD, Younus F, Coppin C, Meirelles T, Lethier M, Pandey G, Ollis DL and Oakeshott JG <2 more author(s)>
    Ref: Proc Natl Acad Sci U S A, 110:10177, 2013 : PubMed

            



Representative scheme of Carb_B_Arthropoda structure and an image from PDBsum server



Databases

PDB-Sum5IKX Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP5IKX Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP5IKX Structural Classification Of Protein - SCOP server
PROTEOPEDIA5ikx 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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