Tree Display

AceDB Schema

XML Display


Structure Report for: 6FLD

Name|Carbamylated Torpedo californica acetylcholineterase bound to uncharged hybrid reactivator Tacrine-pyridinealdoxime-1
Revelation date|29-Aug-2018
Family|ACHE: there are 538 genes in this family, 315 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
De la Mora, E., Santoni, G., de Souza, J., Sussman, J., Silman, I., Baati, R., Weik, M., Nachon, F.
Ligand|Reactivator: Tacrine-pyridinealdoxime-1 Ligand in structure: Ligplot


    Title: Structure-Based Optimization of Nonquaternary Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents
    Santoni G, de Sousa J, De la Mora E, Dias J, Jean L, Sussman JL, Silman I, Renard PY, Brown RCD and Nachon F <2 more author(s)>
    Ref: Journal of Medicinal Chemistry, 61:7630, 2018 : PubMed


Representative scheme of ACHE structure and an image from PDBsum server


PDB-Sum6FLD Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP6FLD Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP6FLD Structural Classification Of Protein - SCOP server
PROTEOPEDIA6fld 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

Acknowledgements and disclaimer