6MVD

Name : Crystal structure of human Lecithin:cholesterol acyltransferase (LCAT) in complex with isopropyl dodec-11-enylfluorophosphonate (IDFP) and a small molecule activator supersedes 6DTJ

Revelation date : 05-Dec-2018

Family : PC-sterol_acyltransferase

Gene_locus : human-LCAT

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Manthei, K.A., Yang, S., Baljinnyam, B., Chang, L., Glukhova, A., Yuan, W., Freeman, L.A., Shen, M., Maloney, D.J., Schwendeman, A., Remaley, A.T., Jadhav, A., Tesmer, J.J.G. There is a preprint available at Biorxiv<\/A>

Ligand :

References (1)

Title : Molecular basis for activation of lecithin:cholesterol acyltransferase by a compound that increases HDL cholesterol - Manthei_2018_Elife_7_
Author(s) : Manthei KA , Yang SM , Baljinnyam B , Chang L , Glukhova A , Yuan W , Freeman LA , Maloney DJ , Schwendeman A , Remaley AT , Jadhav A , Tesmer JJ
Ref : Elife , 7 : , 2018
Abstract : Manthei_2018_Elife_7_
ESTHER : Manthei_2018_Elife_7_
PubMedSearch : Manthei_2018_Elife_7_
PubMedID: 30479275
Gene_locus related to this paper: human-LCAT

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

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