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Structure Report for: 6O5R

Name|Room temperature structure of binary complex of native hAChE with oxime reactivator RS-170B
Revelation date|29-May-2019
Family|ACHE: there are 538 genes in this family, 315 structure(s)
Gene_locus|human-ACHE
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Gerlits, O., Kovalevsky, A., Radic, Z.
Ligand|Reactivator: RS170B Ligand in structure: Ligplot


Reference

    Title: Productive reorientation of a bound oxime reactivator revealed in room temperature X-ray structures of native and VX-inhibited human acetylcholinesterase
    Gerlits O, Kong X, Cheng X, Wymore T, Blumenthal DK, Taylor P, Radic Z, Kovalevsky A
    Ref: Journal of Biological Chemistry, 294:10607, 2019 : PubMed

            



Representative scheme of ACHE structure and an image from PDBsum server



Databases

PDB-Sum6O5R Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP6O5R Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP6O5R Structural Classification Of Protein - SCOP server
PROTEOPEDIA6o5r 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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