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Structure Report for: 6TT0

Name|Crystal structure of Torpedo californica ACHE complexed with MC1420
Revelation date|10-Jun-2020
Family|ACHE: there are 541 genes in this family, 315 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Marco Catto, Leonardo Pisani, Eugenio De La Mora, Benny Danilo Belviso, Giuseppe Felice, Felice Mangiatordi, Andrea Pinto, Annalisa De Palma, Nunzio Denora, Rocco Caliandro, Jacques-Philippe Colletier, Israel Silman, Orazio Nicolotti, and Cosimo Damiano Altomare
Ligand|Inhibitor: MC1420 Ligand in structure: Ligplot


    Title: Chiral Separation, X-ray Structure, and Biological Evaluation of a Potent and Reversible Dual Binding Site AChE Inhibitor
    Catto M, Pisani L, De la Mora E, Belviso BD, Mangiatordi GF, Pinto A, Palma A, Denora N, Caliandro R and Altomare CD <3 more author(s)>
    Ref: ACS Med Chem Lett, 11:869, 2020 : PubMed


Representative scheme of ACHE structure and an image from PDBsum server


PDB-Sum6TT0 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP6TT0 Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP6TT0 Structural Classification Of Protein - SCOP server
PROTEOPEDIA6tt0 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

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