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Structure Report for: 6X6C

Name|Cryo-EM structure of NLRP1-DPP9-VbP complex
Revelation date|10-Mar-2021
Family|DPP4N_Peptidase_S9: there are 829 genes in this family, 179 structure(s)
Gene_locus|human-DPP9
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Hollingsworth, L.R., Sharif, H.
Ligand|Inhibitor: Talabostat Ligand in structure: Ligplot


Reference

    Title: DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation
    Hollingsworth LR, Sharif H, Griswold AR, Fontana P, Mintseris J, Dagbay KB, Paulo JA, Gygi SP, Bachovchin DA, Wu H
    Ref: Nature, :, 2021 : PubMed

            

    Title: DPP9 directly sequesters the NLRP1 C-terminus to repress inflammasome activation
    Hollingsworth LR, Sharif H, Griswold AR, Fontana P, Mintseris J, Dagbay KB, Paulo JA, Gygi SP, Bachovchin DA, Wu
    Ref: Biorxiv, :, 2020 : PubMed

            



Representative scheme of DPP4N_Peptidase_S9 structure and an image from PDBsum server

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Databases

PDB-Sum6X6C Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP6X6C Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP6X6C Structural Classification Of Protein - SCOP server
PROTEOPEDIA6x6c 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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