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Structure Report for: 6XYU

Name|Update AChE from Drosophila Melanogaster complex with tacrine derivative 9-(3-iodobenzylamino)-1,2,3,4-tetrahydroacridine (1QON)
Revelation date|18-Mar-2020
Family|ACHE: there are 538 genes in this family, 315 structure(s)
Gene_locus|drome-ACHE
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Nachon, F., Sussman, J.L.
Ligand|Inhibitor: ZAI Ligand in structure: Ligplot


Reference

    Title: A Second Look at the Crystal Structures of Drosophila melanogaster Acetylcholinesterase in Complex with Tacrine Derivatives Provides Insights Concerning Catalytic Intermediates and the Design of Specific Insecticides
    Nachon F, Rosenberry TL, Silman I, Sussman JL
    Ref: Molecules, 25:1198, 2020 : PubMed

            



Representative scheme of ACHE structure and an image from PDBsum server



Databases

PDB-Sum6XYU Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP6XYU Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP6XYU Structural Classification Of Protein - SCOP server
PROTEOPEDIA6xyu 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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