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Structure Report for: 7BO3

Name|Human Butyrylcholinesterase in complex with N-(2-(1H-Indol-3-yl)ethyl)-2-cycloheptyl-N-methylethan-1-amine
Revelation date|02-Mar-2022
Family|BCHE: there are 91 genes in this family, 91 structure(s)
Gene_locus|human-BCHE
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Brazzolotto, X.,Meden, A.,Knez, D.,Nachon, F.,Gobec, S.
Ligand|Inhibitor: IA4-7BO3 Ligand in structure: Ligplot


Reference

    Title: From tryptophan-based amides to tertiary amines: Optimization of a butyrylcholinesterase inhibitor series
    Meden A, Knez D, Brazzolotto X, Nachon F, Dias J, Svete J, Stojan J, Groselj U, Gobec S
    Ref: Eur Journal of Medicinal Chemistry, 230:114248, 2022 : PubMed

            



Representative scheme of BCHE structure and an image from PDBsum server



Databases

PDB-Sum7BO3 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP7BO3 Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP7BO3 Structural Classification Of Protein - SCOP server
PROTEOPEDIA7bo3 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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