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Structure Report for: 7EBA

Name|Soluble epoxide hydrolase in complex with kurarinone
Revelation date|09-Mar-2022
Family|Epoxide_hydrolase: there are 1154 genes in this family, 155 structure(s)
Gene_locus|human-EPHX2
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Cheng-Peng Sun, Jun-Jun Zhou, Zhen-Long Yu, Xiao-Kui Huo, Juan Zhang, Christophe Morisseau, Bruce D Hammock, Xiao-Chi Ma
Ligand|Inhibitor: Kurarinone Ligand in structure: Ligplot


Reference

    Title: Kurarinone alleviated Parkinson's disease via stabilization of epoxyeicosatrienoic acids in animal model
    Sun CP, Zhou JJ, Yu ZL, Huo XK, Zhang J, Morisseau C, Hammock BD, Ma XC
    Ref: Proc Natl Acad Sci U S A, 119:, 2022 : PubMed

            



Representative scheme of Epoxide_hydrolase structure and an image from PDBsum server

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Databases

PDB-Sum7EBA Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP7EBA Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP7EBA Structural Classification Of Protein - SCOP server
PROTEOPEDIA7eba 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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