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Structure Report for: 7L4U

Name|Crystal structure of human monoacylglycerol lipase in complex with compound XP7-7L4U
Revelation date|11-Aug-2021
Family|Monoglyceridelipase_lysophospholip: there are 1179 genes in this family, 26 structure(s)
Gene_locus|human-MGLL
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Qin, L.,Lane, W.,Skene, R.J., Dougan, D.
Ligand|Inhibitor: XP7-7L4U Ligand in structure: Ligplot


Reference

    Title: Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl Moiety
    Ikeda S, Sugiyama H, Tokuhara H, Murakami M, Nakamura M, Oguro Y, Aida J, Morishita N, Sogabe S and Kamata M <9 more author(s)>
    Ref: Journal of Medicinal Chemistry, :, 2021 : PubMed

            



Representative scheme of Monoglyceridelipase_lysophospholip structure and an image from PDBsum server

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Databases

PDB-Sum7L4U Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP7L4U Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP7L4U Structural Classification Of Protein - SCOP server
PROTEOPEDIA7l4u 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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