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Structure Report for: 7PRM

Name|Crystal structure of human monoglyceride lipase with compound 13, YH149
Revelation date|16-Feb-2022
Family|Monoglyceridelipase_lysophospholip: there are 1179 genes in this family, 26 structure(s)
Gene_locus|human-MGLL
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Grether, U.,Gobbi, L.,Kuhn, B.,Collin, L.,Leibrock, L.,Heer, D.,Wittwer, M.,Benz, J.
Ligand|Inhibitor: YH149 Ligand in structure: Ligplot


Reference

    Title: Development of High Brain-Penetrant and Reversible Monoacylglycerol Lipase PET Tracers for Neuroimaging
    He Y, Schild M, Grether U, Benz J, Leibrock L, Heer D, Topp A, Collin L, Kuhn B and Mu L <4 more author(s)>
    Ref: Journal of Medicinal Chemistry, :, 2022 : PubMed

            



Representative scheme of Monoglyceridelipase_lysophospholip structure and an image from PDBsum server

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Databases

PDB-Sum7PRM Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP7PRM Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP7PRM Structural Classification Of Protein - SCOP server
PROTEOPEDIA7prm 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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