Structure

Tree Display

AceDB Schema

XML Display

Feedback

Structure Report for: 7R3C

Name|Mus musculus Acetylcholinesterase inhibited by VX in complex with reactivator 4-methyl-3-nitrobenzamido-pentyl-PAM-7d
Revelation date|27-Apr-2022
Family|ACHE: there are 538 genes in this family, 315 structure(s)
Gene_locus|mouse-ACHE
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Ligand|Inhibitor: VX Ligand in structure: Ligplot Reactivator: 4-methyl-3-nitrobenzamido-pentyl-PAM-7d Ligand in structure: Ligplot


Reference

    Title: Broad-spectrum antidote discovery by untangling the reactivation mechanism of nerve agent inhibited acetylcholinesterase
    Lindgren C, Forsgren N, Hoster N, Akfur C, Artursson E, Edvinsson L, Svensson R, Worek F, Ekstrom, Linusson A
    Ref: Chemistry, :, 2022 : PubMed

            



Representative scheme of ACHE structure and an image from PDBsum server



Databases

PDB-Sum7R3C Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP7R3C Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP7R3C Structural Classification Of Protein - SCOP server
PROTEOPEDIA7r3c 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
webmaster

Acknowledgements and disclaimer