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Structure Report for: 8BTA

Name|Structure of the human Wnt deacylase Notum in complex with ARUK3004308
Revelation date|14-Dec-2022
Family|Pectinacetylesterase-Notum: there are 695 genes in this family, 143 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Zhao, Y.,Jones, E.Y.,Fish, P.
Ligand|Inhibitor: ARUK3004308 Ligand in structure: Ligplot


    Title: Designed switch from covalent to non-covalent inhibitors of carboxylesterase Notum activity
    Atkinson BN, Willis NJ, Zhao Y, Patel C, Frew S, Costelloe K, Magno L, Svensson F, Jones EY, Fish PV
    Ref: Eur Journal of Medicinal Chemistry, 251:115132, 2023 : PubMed


Representative scheme of Pectinacetylesterase-Notum structure and an image from PDBsum server

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PDB-Sum8BTA Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP8BTA Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP8BTA Structural Classification Of Protein - SCOP server
PROTEOPEDIA8bta 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

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