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Substrate Report for: 4-methylumbelliferyl-caprylate

General
Type Coumarin, Octanoate
Chemical_Nomenclature (4-methyl-2-oxochromen-7-yl) octanoate
Canonical SMILES CCCCCCCC(=O)OC1=CC2=C(C=C1)C(=CC(=O)O2)C
InChI InChI=1S/C18H22O4/c1-3-4-5-6-7-8-17(19)21-14-9-10-15-13(2)11-18(20)22-16(15)12-14/h9-12H,3-8H2,1-2H3
InChIKey WZEWYQWWSCVHCP-UHFFFAOYSA-N
Other name(s) 4-Methylumbelliferyl caprylate ; 4-Methylumbelliferyl-octanoate ; 4-Methylumbelliferyl octanoate ; 4-Methylumbelliferone caprylate ; 4-Methylumbelliferone-caprylate ; 4-Methylumbelliferone octanoate ; 4-Methylumbelliferone-octanoate ; 4-MU-Caprylate ; 4MU-Caprylate ; 4MU-C8 ; 4MU-Octanoate ; 4-methyl-2-oxo-2H-chromen-7-yl octanoate ; 4-methyl-2-oxochromen-7-yl octanoate ; AO-548/41203646 ; MUCAP
________________________________________________________________________________________________
MW|302.36
Formula|C18H22O4
CAS_number|20671-66-3
PubChem|3082165
UniChem|WZEWYQWWSCVHCP-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | 4-methylumbelliferyl-caprylate ligand of proteins in family: Bacterial_lip_FamI.5, Plant_carboxylesterase, Plasmodium_subtelomeric_PST-A
Protein | bactc-lipas, plafa-PF10.0379

References:
Search PubMed for references concerning: 4-methylumbelliferyl-caprylate
    Title: The Antimalarial Natural Product Salinipostin A Identifies Essential alpha/beta Serine Hydrolases Involved in Lipid Metabolism in P. falciparum Parasites
    Yoo E, Schulze CJ, Stokes BH, Onguka O, Yeo T, Mok S, Gnadig NF, Zhou Y, Kurita K and Bogyo M <11 more author(s)>
    Ref: Cell Chemical Biology, 27:143, 2020 : PubMed

            

    Title: Probing the roles of two tryptophans surrounding the unique zinc coordination site in lipase family I.5
    Timucin E, Cousido-Siah A, Mitschler A, Podjarny A, Sezerman OU
    Ref: Proteins, 84:129, 2016 : PubMed

            

    Title: High-resolution crystal structure of plant carboxylesterase AeCXE1, from Actinidia eriantha, and its complex with a high-affinity inhibitor paraoxon
    Ileperuma NR, Marshall SD, Squire CJ, Baker HM, Oakeshott JG, Russell RJ, Plummer KM, Newcomb RD, Baker EN
    Ref: Biochemistry, 46:1851, 2007 : PubMed