Type : Prostaglandin || Acyl-Glycerol || Cannabinoid-Receptor-ligand || Natural
Chemical_Nomenclature : 2,3-dihydroxypropyl (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoate
Canonical SMILES : CCCCCC(C=CC1C(CC(=O)C1CC=CCCCC(=O)OCC(CO)O)O)O
InChI : InChI=1S\/C23H38O7\/c1-2-3-6-9-17(25)12-13-20-19(21(27)14-22(20)28)10-7-4-5-8-11-23(29)30-16-18(26)15-24\/h4,7,12-13,17-20,22,24-26,28H,2-3,5-6,8-11,14-16H2,1H3\/b7-4-,13-12+\/t17-,18?,19+,20+,22+\/m0\/s1
InChIKey : RJXVYMMSQBYEHN-LVXZDWGESA-N
Other name(s) : PGE2-G, Prostaglandin E2-1-glyceryl ester, Prostaglandin PGE(,2) 1-glycerol, CHEBI:90230, 1(3)-glyceryl-PGE2
Title : Human leukocytes differentially express endocannabinoid-glycerol lipases and hydrolyze 2-arachidonoyl-glycerol and its metabolites from the 15-lipoxygenase and cyclooxygenase pathways - Turcotte_2019_J.Leukoc.Biol_106_1337 |
Author(s) : Turcotte C , Dumais E , Archambault AS , Martin C , Blanchet MR , Bissonnette E , Boulet LP , Laviolette M , Di Marzo V , Flamand N |
Ref : J Leukoc Biol , 106 :1337 , 2019 |
Abstract : Turcotte_2019_J.Leukoc.Biol_106_1337 |
ESTHER : Turcotte_2019_J.Leukoc.Biol_106_1337 |
PubMedSearch : Turcotte_2019_J.Leukoc.Biol_106_1337 |
PubMedID: 31556464 |
Gene_locus related to this paper: human-ABHD6 , human-ABHD12 , human-ABHD16A , human-CES1 , human-LYPLA2 , human-PPT1 |
Title : Robust Hydrolysis of Prostaglandin Glycerol Esters by Human Monoacylglycerol Lipase (MAGL) - Savinainen_2014_Mol.Pharmacol_86_522 |
Author(s) : Savinainen JR , Kansanen E , Pantsar T , Navia-Paldanius D , Parkkari T , Lehtonen M , Laitinen T , Nevalainen T , Poso A , Levonen AL , Laitinen JT |
Ref : Molecular Pharmacology , 86 :522 , 2014 |
Abstract : Savinainen_2014_Mol.Pharmacol_86_522 |
ESTHER : Savinainen_2014_Mol.Pharmacol_86_522 |
PubMedSearch : Savinainen_2014_Mol.Pharmacol_86_522 |
PubMedID: 25140003 |
Gene_locus related to this paper: human-ABHD6 , human-ABHD12 , human-MGLL |
Title : Possible involvement of brain prostaglandin E2 and prostanoid EP3 receptors in prostaglandin E2 glycerol ester-induced activation of central sympathetic outflow in the rat - Shimizu_2014_Neuropharmacol_82_19 |
Author(s) : Shimizu T , Tanaka K , Nakamura K , Taniuchi K , Yawata T , Higashi Y , Ueba T , Dimitriadis F , Shimizu S , Yokotani K , Saito M |
Ref : Neuropharmacology , 82 :19 , 2014 |
Abstract : Shimizu_2014_Neuropharmacol_82_19 |
ESTHER : Shimizu_2014_Neuropharmacol_82_19 |
PubMedSearch : Shimizu_2014_Neuropharmacol_82_19 |
PubMedID: 24657150 |
Title : Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes\/macrophages by activated organophosphorus insecticides: role of carboxylesterases 1 and 2 - Xie_2010_Chem.Res.Toxicol_23_1890 |
Author(s) : Xie S , Borazjani A , Hatfield MJ , Edwards CC , Potter PM , Ross MK |
Ref : Chemical Research in Toxicology , 23 :1890 , 2010 |
Abstract : Xie_2010_Chem.Res.Toxicol_23_1890 |
ESTHER : Xie_2010_Chem.Res.Toxicol_23_1890 |
PubMedSearch : Xie_2010_Chem.Res.Toxicol_23_1890 |
PubMedID: 21049984 |
Title : A physiological role for endocannabinoid-derived products of cyclooxygenase-2-mediated oxidative metabolism - Guindon_2008_Br.J.Pharmacol_153_1341 |
Author(s) : Guindon J , Hohmann AG |
Ref : British Journal of Pharmacology , 153 :1341 , 2008 |
Abstract : Guindon_2008_Br.J.Pharmacol_153_1341 |
ESTHER : Guindon_2008_Br.J.Pharmacol_153_1341 |
PubMedSearch : Guindon_2008_Br.J.Pharmacol_153_1341 |
PubMedID: 18297102 |