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Acetylcholine

General

Type : Acetate || Trimethylammonium || Natural || Choline ester

Chemical_Nomenclature : 2-(Acetyloxy)-N,N,N,-trimethylethanaminium

Canonical SMILES : CC(=O)OCC[N+](C)(C)C

InChI : InChI=1S\/C7H16NO2\/c1-7(9)10-6-5-8(2,3)4\/h5-6H2,1-4H3\/q+1

InChIKey : OIPILFWXSMYKGL-UHFFFAOYSA-N

Other name(s) : Choline acetate,     O-Acetylcholine,     Acetyl choline ion,     Choline acetate (ester),     Acetylcholinum

MW : 146.20

Formula : C7H16NO2

CAS_number : 51-84-3

PubChem :

UniChem :

Iuphar :

Target

Families : ACHE, BCHE, Cholinesterase, Cholinesterase-like

References (6)

Title : Substrate and product trafficking through the active center gorge of acetylcholinesterase analyzed by crystallography and equilibrium binding - Bourne_2006_J.Biol.Chem_281_29256
Author(s) : Bourne Y , Radic Z , Sulzenbacher G , Kim E , Taylor P , Marchot P
Ref : Journal of Biological Chemistry , 281 :29256 , 2006
Abstract : Bourne_2006_J.Biol.Chem_281_29256
ESTHER : Bourne_2006_J.Biol.Chem_281_29256
PubMedSearch : Bourne_2006_J.Biol.Chem_281_29256
PubMedID: 16837465
Gene_locus related to this paper: mouse-ACHE

Title : Structure of acetylcholinesterase complexed with the nootropic alkaloid, (-)-huperzine A - Raves_1997_Nat.Struct.Biol_4_57
Author(s) : Raves ML , Harel M , Pang YP , Silman I , Kozikowski AP , Sussman JL
Ref : Nat Struct Biol , 4 :57 , 1997
Abstract : Raves_1997_Nat.Struct.Biol_4_57
ESTHER : Raves_1997_Nat.Struct.Biol_4_57
PubMedSearch : Raves_1997_Nat.Struct.Biol_4_57
PubMedID: 8989325
Gene_locus related to this paper: torca-ACHE

Title : Atomic structure of acetylcholinesterase from Torpedo californica: a prototypic acetylcholine-binding protein - Sussman_1991_Science_253_872
Author(s) : Sussman JL , Harel M , Frolow F , Oefner C , Goldman A , Toker L , Silman I
Ref : Science , 253 :872 , 1991
Abstract : Sussman_1991_Science_253_872
ESTHER : Sussman_1991_Science_253_872
PubMedSearch : Sussman_1991_Science_253_872
PubMedID: 1678899
Gene_locus related to this paper: torca-ACHE

Title : Genetic variants of human serum cholinesterase influence metabolism of the muscle relaxant succinylcholine. - Lockridge_1990_Pharmacol.Ther_47_35
Author(s) : Lockridge O
Ref : Pharmacol Ther , 47 :35 , 1990
Abstract : Lockridge_1990_Pharmacol.Ther_47_35
ESTHER : Lockridge_1990_Pharmacol.Ther_47_35
PubMedSearch : Lockridge_1990_Pharmacol.Ther_47_35
PubMedID: 2195556
Gene_locus related to this paper: human-BCHE

Title : Hydrolysis by acetylcholinesterase. Apparent molal volumes and trimethyl and methyl subsites -
Author(s) : Hasan FB , Cohen SG , Cohen JB
Ref : Journal of Biological Chemistry , 255 :3898 , 1980
PubMedID: 7372658

Title : The action of normal and atypical cholinesterase of human serum upon a series of esters of choline -
Author(s) : Davies RO , Marton AV , Kalow W
Ref : Canadian Journal of Biochemistry & Pharmacology , 38 :545 , 1960
PubMedID: 13814417