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Substrate Report for: Astexin3-dC4

Lasso peptides are a large family of natural products formed by a side chain to backbone macrocyclization, resembling a knotted lasso. They have antibacterial activity. Astexin-3 treated with carboxypeptidase Y yields a truncated lasso peptide that lacked the C-terminal 4 amino acids E8RUP8_ASTEC ADU14098


General
Type Peptide
Chemical_Nomenclature GPTPMVGLDSVSGQYWDQHA(PLAD)
Canonical SMILES
InChI
InChIKey
Other name(s)
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MW|
Formula|
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Target
Families | Astexin3-dC4 ligand of proteins in family: ACPH_Peptidase_S9
Stucture | 1 structure: 5TXE: AtxE2 Isopeptidase - S527A Variant with Astexin3-dC4 Bound
Protein | astec-e8rup5

References:
Search PubMed for references concerning: Astexin3-dC4
    Title: Structure of the Lasso Peptide Isopeptidase Identifies a Topology for Processing Threaded Substrates
    Chekan JR, Koos JD, Zong C, Maksimov MO, Link AJ, Nair SK
    Ref: Journal of the American Chemical Society, 138:16452, 2016 : PubMed