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Substrate Report for: Cyclohexene-oxide

Cyclohexene oxide (CHO) is a monomer intermediate used in the synthesis of pesticides, pharmaceuticals, and perfumes


General
Type Epoxide
Chemical_Nomenclature (1S,6R)-7-oxabicyclo[4.1.0]heptane
Canonical SMILES C1CCC2C(C1)O2
InChI InChI=1S/C6H10O/c1-2-4-6-5(3-1)7-6/h5-6H,1-4H2/t5-,6+
InChIKey ZWAJLVLEBYIOTI-OLQVQODUSA-N
Other name(s) Cyclohexene oxide ; 1,2-Epoxycyclohexane ; 7EX ; Cis-Cyclohexene Oxide ; UNII-1XYE04C550 ; 1XYE04C550 ; (1S,6R)-7-oxabicyclo[4.1.0]heptane ; CCRIS 1227 ; HSDB 5422 ; 7-oxa-bicyclo[4.1.0]heptan ; epoxycyclohexane ; ECH
________________________________________________________________________________________________
MW|98.14
Formula|C6H10O
CAS_number|
PubChem|637978
UniChem|ZWAJLVLEBYIOTI-OLQVQODUSA-N
IUPHAR|
Wikipedia|

Target
Families | Cyclohexene-oxide ligand of proteins in family: CFTR-inhibitory-factor_Cif, Epoxide_hydrolase
Stucture | 2 structures: 5TND, 5TNS
Protein | pseae-PA2934, 9bact-a0a1u9wz52, 9bact-a0a1u9wz58, corsp-cEH

References:
Search PubMed for references concerning: Cyclohexene-oxide

1 more
    Title: New Thermophilic alpha/beta Class Epoxide Hydrolases Found in Metagenomes From Hot Environments
    Ferrandi EE, Sayer C, De Rose SA, Guazzelli E, Marchesi C, Saneei V, Isupov MN, Littlechild JA, Monti D
    Ref: Front Bioeng Biotechnol, 6:144, 2018 : PubMed

            

    Title: Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase
    Hvorecny KL, Bahl CD, Kitamura S, Lee KSS, Hammock BD, Morisseau C, Madden DR
    Ref: Structure, 25:697, 2017 : PubMed

            

    Title: Oviductal microsomal epoxide hydrolase (EPHX1) reduces reactive oxygen species (ROS) level and enhances preimplantation mouse embryo development
    Cheong AW, Lee YL, Liu WM, Yeung WS, Lee KF
    Ref: Biol Reprod, 81:126, 2009 : PubMed