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Substrate Report for: D-luciferin-methyl-ester

luciferin derivatives for use in bioluminescence enhanced enzyme substrate



General
Type: Benzothiazol
Chemical_Nomenclature: methyl (4S)-2-(6-hydroxy-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylate
Canonical SMILES: COC(=O)C1CSC(=N1)C2=NC3=C(S2)C=C(C=C3)O
InChI: InChI=1S/C12H10N2O3S2/c1-17-12(16)8-5-18-10(14-8)11-13-7-3-2-6(15)4-9(7)19-11/h2-4,8,15H,5H2,1H3/t8-/m1/s1
InChIKey: PULFPBAWBRMDDC-MRVPVSSYSA-N
Other name(s): DME ; D-Luciferin,6'-Methyl Ether ; D-Luciferin methyl ; D-luciferin methyl ester ; CHEMBL3427171 ; SCHEMBL12941013 ; ZINC149748264
MW: 294.34
Formula: C12H10N2O3S2
CAS_number:
PubChem: 135424806
IUPHAR:
Wikipedia:

Target families
D-luciferin-methyl-ester ligand of proteins in family: Carb_B_Chordata
No structure

Protein target
Enzyme: human-CES1

References
Search PubMed for references concerning: D-luciferin-methyl-ester

3 more
    Title: Discovery of natural pentacyclic triterpenoids as potent and selective inhibitors against human carboxylesterase 1
    Song PF, Zhu YD, Ma HY, Wang YN, Wang DD, Zou LW, Ge GB, Yang L
    Ref: Fitoterapia, 137:104199, 2019 : PubMed

            

    Title: A new type of ultrasensitive bioluminogenic enzyme substrates. I. Enzyme substrates with D-luciferin as leaving group
    Miska W, Geiger R
    Ref: Biol Chem Hoppe Seyler, 369:407, 1988 : PubMed

            

    Title: Synthesis and characterization of luciferin derivatives for use in bioluminescence enhanced enzyme immunoassays. New ultrasensitive detection systems for enzyme immunoassays, I
    Miska W, Geiger R
    Ref: J Clinical Chemistry Clinical Biochemistry, 25:23, 1987 : PubMed