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Substrate Report for: DPPO

Improved radiolabeled substrates for soluble epoxide hydrolase


General
Type Epoxide
Chemical_Nomenclature 2-benzyl-3-phenyloxirane
Canonical SMILES C1=CC=C(C=C1)CC2C(O2)C3=CC=CC=C3
InChI InChI=1S/C15H14O/c1-3-7-12(8-4-1)11-14-15(16-14)13-9-5-2-6-10-13/h1-10,14-15H,11H2
InChIKey ZMEQMWLSJBXCMR-UHFFFAOYSA-N
Other name(s) 2-benzyl-3-phenyloxyrane ; SCHEMBL2509748 ; 1,3-Diphenyl-2,3-epoxypropane ; CTK5J6210 ; MolPort-004-303-499
________________________________________________________________________________________________
MW|210.27
Formula|C15H14O
CAS_number|
PubChem|12385029
UniChem|ZMEQMWLSJBXCMR-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | DPPO ligand of proteins in family: Epoxide_hydrolase, CFTR-inhibitory-factor_Cif

References:
Search PubMed for references concerning: DPPO
    Title: Substrate and inhibitor selectivity, and biological activity of an epoxide hydrolase from Trichoderma reesei
    de Oliveira GS, Adriani PP, Wu H, Morisseau C, Hammock BD, Chambergo FS
    Ref: Mol Biol Rep, 46:371, 2019 : PubMed

            

    Title: Visualizing the Mechanism of Epoxide Hydrolysis by the Bacterial Virulence Enzyme Cif
    Bahl CD, Hvorecny KL, Morisseau C, Gerber SA, Madden DR
    Ref: Biochemistry, 55:788, 2016 : PubMed

            

    Title: Improved radiolabeled substrates for soluble epoxide hydrolase
    Borhan B, Mebrahtu T, Nazarian S, Kurth MJ, Hammock BD
    Ref: Analytical Biochemistry, 231:188, 1995 : PubMed