Esmolol

General

Type : Not A\/B H target || Drug || Propionate

Chemical_Nomenclature : methyl 3-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]propanoate

Canonical SMILES : CC(C)NCC(COC1=CC=C(C=C1)CCC(=O)OC)O

InChI : InChI=1S\/C16H25NO4\/c1-12(2)17-10-14(18)11-21-15-7-4-13(5-8-15)6-9-16(19)20-3\/h4-5,7-8,12,14,17-18H,6,9-11H2,1-3H3

InChIKey : AQNDDEOPVVGCPG-UHFFFAOYSA-N

Other name(s) : (+-)-Esmolol,     Brevibloc,     CHEBI:88206,     CHEMBL768,     SCHEMBL3605,     DB00187


MW : 295.37

Formula : C16H25NO4

CAS_number : 81147-92-4 || 103598-03-4

PubChem :

UniChem :

Iuphar :

References (5)

Title : Esterases Involved in the Rapid Bioconversion of Esmolol after Intravenous Injection in Humans - Imai_2022_Biol.Pharm.Bull_45_1544
Author(s) : Imai T , Isozaki M , Ohura K
Ref : Biol Pharm Bull , 45 :1544 , 2022
Abstract : Imai_2022_Biol.Pharm.Bull_45_1544
ESTHER : Imai_2022_Biol.Pharm.Bull_45_1544
PubMedSearch : Imai_2022_Biol.Pharm.Bull_45_1544
PubMedID: 36184514

Title : Use of low-dose neostigmine intravenously in the treatment of thyroid storm-induced severe tachycardia in patient during huge pelvic mass resection: A case report and review of literature - Zhang_2018_Medicine.(Baltimore)_97_e0300
Author(s) : Zhang X , Jiang H , Li S , Luo A , Zhao Y
Ref : Medicine (Baltimore) , 97 :e0300 , 2018
Abstract : Zhang_2018_Medicine.(Baltimore)_97_e0300
ESTHER : Zhang_2018_Medicine.(Baltimore)_97_e0300
PubMedSearch : Zhang_2018_Medicine.(Baltimore)_97_e0300
PubMedID: 29620652

Title : Cholinesterase inhibition by potato glycoalkaloids slows mivacurium metabolism - McGehee_2000_Anesthesiology_93_510
Author(s) : McGehee DS , Krasowski MD , Fung DL , Wilson B , Gronert GA , Moss J
Ref : Anesthesiology , 93 :510 , 2000
Abstract : McGehee_2000_Anesthesiology_93_510
ESTHER : McGehee_2000_Anesthesiology_93_510
PubMedSearch : McGehee_2000_Anesthesiology_93_510
PubMedID: 10910502

Title : Neuromuscular interactions between mivacurium and esmolol in rabbits - Kim_1998_Anaesthesia_53_140
Author(s) : Kim KS , Kim KH , Shin WJ , Yoo HK
Ref : Anaesthesia , 53 :140 , 1998
Abstract : Kim_1998_Anaesthesia_53_140
ESTHER : Kim_1998_Anaesthesia_53_140
PubMedSearch : Kim_1998_Anaesthesia_53_140
PubMedID: 9534636

Title : Biochemical properties of blood esmolol esterase - Quon_1985_Drug.Metab.Dispos_13_420
Author(s) : Quon CY , Stampfli HF
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 13 :420 , 1985
Abstract : Quon_1985_Drug.Metab.Dispos_13_420
ESTHER : Quon_1985_Drug.Metab.Dispos_13_420
PubMedSearch : Quon_1985_Drug.Metab.Dispos_13_420
PubMedID: 2863104