Ethyl-Flurbiprofen
General
Type : Not A\/B H target || Drug || Pro-Drug || Propionate || Alkyl ester
Chemical_Nomenclature : ethyl 2-(3-fluoro-4-phenylphenyl)propanoate
Canonical SMILES : CCOC(=O)C(C)C1=CC(=C(C=C1)C2=CC=CC=C2)F
InChI : InChI=1S\/C17H17FO2\/c1-3-20-17(19)12(2)14-9-10-15(16(18)11-14)13-7-5-4-6-8-13\/h4-12H,3H2,1-2H3
InChIKey : JIYXQCWLSQSIJV-UHFFFAOYSA-N
Other name(s) : Flurbiprofen Ethyl Ester, Ethyl Flurbiprofen, SCHEMBL9555720
Target
Families : Hormone-sensitive_lipase_like, Bacterial_lip_FamI.3, Canar_LipB
References (6)
| Title : Enhanced Production of (S)-2-arylpropionic Acids by Protein Engineering and Whole-Cell Catalysis - Liu_2021_Front.Bioeng.Biotechnol_9_697677 |
| Author(s) : Liu X , Zhao M , Fan X , Fu Y |
| Ref : Front Bioeng Biotechnol , 9 :697677 , 2021 |
| Abstract : Liu_2021_Front.Bioeng.Biotechnol_9_697677 |
| ESTHER : Liu_2021_Front.Bioeng.Biotechnol_9_697677 |
| PubMedSearch : Liu_2021_Front.Bioeng.Biotechnol_9_697677 |
| PubMedID: 34307324 |
| Gene_locus related to this paper: 9zzzz-Est924 |
| Title : Synthesis of L-Ascorbyl Flurbiprofenate by Lipase-Catalyzed Esterification and Transesterification Reactions - Xin_2017_Biomed.Res.Int_2017_5751262 |
| Author(s) : Xin JY , Sun LR , Chen SM , Wang Y , Xia CG |
| Ref : Biomed Res Int , 2017 :5751262 , 2017 |
| Abstract : Xin_2017_Biomed.Res.Int_2017_5751262 |
| ESTHER : Xin_2017_Biomed.Res.Int_2017_5751262 |
| PubMedSearch : Xin_2017_Biomed.Res.Int_2017_5751262 |
| PubMedID: 28421196 |
| Title : Direct enantioselective HPLC monitoring of lipase-catalyzed kinetic resolution of flurbiprofen - Ghanem_2010_Chirality_22_597 |
| Author(s) : Ghanem A |
| Ref : Chirality , 22 :597 , 2010 |
| Abstract : Ghanem_2010_Chirality_22_597 |
| ESTHER : Ghanem_2010_Chirality_22_597 |
| PubMedSearch : Ghanem_2010_Chirality_22_597 |
| PubMedID: 19899153 |
| Title : R-stereopreference analysis of lipase Novozym 435 in kinetic resolution of flurbiprofen - Zhang_2007_Chirality_19_245 |
| Author(s) : Zhang HY , Wang X , Ching CB |
| Ref : Chirality , 19 :245 , 2007 |
| Abstract : Zhang_2007_Chirality_19_245 |
| ESTHER : Zhang_2007_Chirality_19_245 |
| PubMedSearch : Zhang_2007_Chirality_19_245 |
| PubMedID: 17094073 |
| Title : Molecular cloning and functional expression of esf gene encoding enantioselective lipase from Serratia marcescens ES-2 for kinetic resolution of optically active (S)-flurbiprofen - Lee_2007_J.Microbiol.Biotechnol_17_74 |
| Author(s) : Lee KW , Bae HA , Lee YH |
| Ref : J Microbiol Biotechnol , 17 :74 , 2007 |
| Abstract : Lee_2007_J.Microbiol.Biotechnol_17_74 |
| ESTHER : Lee_2007_J.Microbiol.Biotechnol_17_74 |
| PubMedSearch : Lee_2007_J.Microbiol.Biotechnol_17_74 |
| PubMedID: 18051356 |
| Gene_locus related to this paper: serma-lipasA |
| Title : Experimental optimization of enzymic kinetic resolution of racemic flurbiprofen - Zhang_2005_Biotechnol.Appl.Biochem_42_67 |
| Author(s) : Zhang HY , Wang X , Ching CB , Wu JC |
| Ref : Biotechnol Appl Biochem , 42 :67 , 2005 |
| Abstract : Zhang_2005_Biotechnol.Appl.Biochem_42_67 |
| ESTHER : Zhang_2005_Biotechnol.Appl.Biochem_42_67 |
| PubMedSearch : Zhang_2005_Biotechnol.Appl.Biochem_42_67 |
| PubMedID: 15651979 |