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Substrate Report for: Irinotecan

General
Type
Chemical_Nomenclature
Canonical SMILES
InChI
InChIKey
Other name(s)
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MW|
Formula|
CAS_number|
PubChem|
UniChem|
IUPHAR|
Wikipedia|

Target
Stucture | 1 structure: 1K4Y: Crystal Structure of Rabbit Liver Carboxylesterase in Complex with 4-piperidino-piperidine (leaving group of the hydrolysis of CPT11 to SN-38)

References:
Search PubMed for references concerning: Irinotecan
    Title: Structural insights into CPT-11 activation by mammalian carboxylesterases
    Bencharit S, Morton CL, Howard-Williams EL, Danks MK, Potter PM, Redinbo MR
    Ref: Nat Struct Biol, 9:337, 2002 : PubMed