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Substrate Report for: PED6

Specificity: PLA2 (this substrate is cleaved by PLA1, but this reaction does not separate the fluorophore from the quencher


General
Type Phospholipid, Phosphoethanolamine, Hexadecanoate, Boron compound
Chemical_Nomenclature [2-[5-[1-difluoroboranyl-5-[(Z)-(3,5-dimethylpyrrol-2-ylidene)methyl]pyrrol-2-yl]pentanoyloxy]-3-[2-[6-(2,4-dinitroanilino)hexanoylamino]ethoxy-hydroxyphosphoryl]oxypropyl] hexadecanoate
Canonical SMILES B(N1C(=CC=C1C=C2C(=CC(=N2)C)C)CCCCC(=O)OC(COC(=O)CCCCCCCCCCCCCCC)COP(=O)(O)OCCNC(=O)CCCCCNC3=C(C=C(C=C3)[N+](=O)[O-])[N+](=O)[O-])(F)F
InChI InChI=1S/C49H74BF2N6O13P/c1-4-5-6-7-8-9-10-11-12-13-14-15-18-24-48(60)68-36-43(71-49(61)25-20-19-22-40-26-27-41(56(40)50(51)52)34-45-38(2)33-39(3)55-45)37-70-72(66,67)69-32-31-54-47(59)23-17-16-21-30-53-44-29-28-42(57(62)63)35-46(44)58(64)65/h26-29,33-35,43,53H,4-25,30-32,36-37H2,1-3H3,(H,54,59)(H,66,67)/b45-34-
InChIKey JZCRSRUOGNAUQN-MBLPBCRHSA-N
Other name(s) D23739 ; N-((6-(2,4-Dinitrophenyl)amino)hexanoyl)-2-(4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Pentanoyl)-1-Hexadecanoyl-sn-Glycero-3-Phosphoethanolamine" ; D-23739
________________________________________________________________________________________________
MW|1034.94
Formula|C49H74BF2N6O13P
CAS_number|
PubChem|10306997
UniChem|JZCRSRUOGNAUQN-MBLPBCRHSA-N
IUPHAR|
Wikipedia|

Target
Families | PED6 ligand of proteins in family: Lipoprotein_Lipase
Protein | human-LIPG

References:
Search PubMed for references concerning: PED6

4 more
    Title: In vivo imaging of zebrafish digestive organ function using multiple quenched fluorescent reporters
    Hama K, Provost E, Baranowski TC, Rubinstein AL, Anderson JL, Leach SD, Farber SA
    Ref: American Journal of Physiology Gastrointest Liver Physiol, 296:G445, 2009 : PubMed

            

    Title: A high-throughput screen for endothelial lipase using HDL as substrate
    Keller PM, Rust T, Murphy DJ, Matico R, Trill JJ, Krawiec JA, Jurewicz A, Jaye M, Harpel M and Schwartz B <1 more author(s)>
    Ref: J Biomol Screen, 13:468, 2008 : PubMed

            

    Title: Fluorometric assays of phospholipase A2 activity with three different substrates in biological samples of patients with schizophrenia
    Lasch J, Willhardt I, Kinder D, Sauer H, Smesny S
    Ref: Clinical Chemistry & Laboratory Medicine, 41:908, 2003 : PubMed