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Substrate Report for: Paranitrophenylbutyrate

General
Type Synthetic, pNP, Chromogen, Butyrate, Water-soluble short chain ester
Chemical_Nomenclature (4-nitrophenyl) butanoate
Canonical SMILES CCCC(=O)OC1=CC=C(C=C1)[N+](=O)[O-]
InChI InChI=1S/C10H11NO4/c1-2-3-10(12)15-9-6-4-8(5-7-9)11(13)14/h4-7H,2-3H2,1H3
InChIKey DVDUMIQZEUTAGK-UHFFFAOYSA-N
Other name(s) pNP-C4 ; pNP-butyrate ; pNP butyrate ; pNPB ; pNP4 ; p-NP butyrate ; 4-Nitrophenyl butyrate ; P-Nitrophenyl butyrate ; P-Nitrophenol butyrate ; Para-Nitrophenyl butyrate ; P-nitrophenyl butanoate
________________________________________________________________________________________________
MW|209.19
Formula|C10H11NO4
CAS_number|2635-84-9
PubChem|75834
UniChem|DVDUMIQZEUTAGK-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | Paranitrophenylbutyrate ligand of proteins in family: Carb_B_Bacteria, Bacterial_lip_FamI.5, Canar_LipB, Lipase_3, GTSAGmotif, Duf_3089, HNLyase_Bact, BioH, Bacterial_Est97, Bacterial_EstLip_FamX, abh_upf00227, 6_AlphaBeta_hydrolase, LYsophospholipase_carboxylesterase, A85-EsteraseD-FGH, Duf_1100-S, Est9X, Polyesterase-lipase-cutinase, Fungal_carboxylesterase_lipase, Hormone-sensitive_lipase_like, Carb_B_Chordata, Cholesterol_esterase, AlphaBeta_hydrolase, ABHD11-Acetyl_transferase, Pectinacetylesterase-Notum, Cutinase
Stucture | 7 structures (e.g. : 7ATF, 5HC2, 5HC0... more)
Protein | bactc-lipas, 9acto-f7ix06, artox-phhyd, burgl-EstC, bovin-balip, rabit-1cxes, psesp-OPH, 9bact-H6BDX1, 9bact-a0a2s1gux0, human-NOTUM, 9delt-EstD11, 9pezi-s4vch4, aspfu-q4x1n0, crysp-Q874E9, fusso-cutas, pyrbr-Q9Y7G8, copci-b9u443, strsw-c9zcr8, humin-cut, human-DAGLA

References:
Search PubMed for references concerning: Paranitrophenylbutyrate

11 more
    Title: Directed evolution of new and improved enzyme functions using an evolutionary intermediate and multidirectional search
    Porter JL, Boon PL, Murray TP, Huber T, Collyer CA, Ollis DL
    Ref: ACS Chemical Biology, 10:611, 2015 : PubMed

            

    Title: Purification and partial characterization of a novel thermophilic carboxylesterase with high mesophilic specific activity
    Wood AN, Fernandez-Lafuente R, Cowan DA
    Ref: Enzyme Microb Technol, 17:816, 1995 : PubMed

            

    Title: Purification and properties of an Arthrobacter oxydans P52 carbamate hydrolase specific for the herbicide phenmedipham and nucleotide sequence of the corresponding gene
    Pohlenz HD, Boidol W, Schuttke I, Streber WR
    Ref: Journal of Bacteriology, 174:6600, 1992 : PubMed

            


artox-phhyd
MutationKmKcatConditionPaper
WT 25 uM -   Pohlenz_1992_J.Bacteriol_174_6600

WT Kinetics
Kinetic parametersKmKcatConditionsPapers
artox-phhyd25 uM- Pohlenz_1992_J.Bacteriol_174_6600