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Substrate Report for: Prostaglandin-D2-Glyceryl-Ester


General
Type: Acyl-Glycerol, Cannabinoid-Receptor-ligand, Natural
Chemical_Nomenclature: 1,3-dihydroxypropan-2-yl (Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxocyclopentyl]hept-5-enoate
Canonical SMILES: CCCCCC(C=CC1C(C(CC1=O)O)CC=CCCCC(=O)OC(CO)CO)O
InChI: InChI=1S/C23H38O7/c1-2-3-6-9-17(26)12-13-20-19(21(27)14-22(20)28)10-7-4-5-8-11-23(29)30-18(15-24)16-25/h4,7,12-13,17-21,24-27H,2-3,5-6,8-11,14-16H2,1H3/b7-4-,13-12+/t17-,19+,20+,21-/m0/s1
InChIKey: OCYWGBZEVKVWBQ-PQGWWSFGSA-N
Other name(s): Prostaglandin D(2) Glyceryl Ester ; 2-Glyceryl-Prostaglandin D2 ; 2-glyceryl-PGD2 ; 9S,15S-dihydroxy-11-oxo-5Z,13E-prostadienoic acid 2-glyceryl ester ; CHEBI:133979 ; prostaglandin D2 2-glyceryl ester
MW: 426.5
Formula: C23H38O7
CAS_number:
PubChem: 24778486
IUPHAR:
Wikipedia:

Target families
Prostaglandin-D2-Glyceryl-Ester ligand of proteins in family: Carb_B_Chordata
No structure

Protein target
Enzyme: human-CES1

References
Search PubMed for references concerning: Prostaglandin-D2-Glyceryl-Ester
    Title: Inactivation of CES1 Blocks Prostaglandin D(2) Glyceryl Ester Catabolism in Monocytes/Macrophages and Enhances Its Anti-inflammatory Effects, Whereas the Pro-inflammatory Effects of Prostaglandin E(2) Glyceryl Ester Are Attenuated
    Scheaffer HL, Borazjani A, Szafran BN, Ross MK
    Ref: ACS Omega, 5:29177, 2020 : PubMed

            

    Title: Metabolism of the endocannabinoids, 2-arachidonylglycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides
    Kozak KR, Crews BC, Morrow JD, Wang LH, Ma YH, Weinander R, Jakobsson PJ, Marnett LJ
    Ref: Journal of Biological Chemistry, 277:44877, 2002 : PubMed