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Substrate Report for: Z-Phe-Arg-AMC

General
Type Benzyloxycarbonyl, Peptide, 7-amido-4-methylcoumarin
Chemical_Nomenclature benzyl N-[1-[[5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Canonical SMILES CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC3=CC=CC=C3)NC(=O)OCC4=CC=CC=C4
InChI InChI=1S/C33H36N6O6/c1-21-17-29(40)45-28-19-24(14-15-25(21)28)37-30(41)26(13-8-16-36-32(34)35)38-31(42)27(18-22-9-4-2-5-10-22)39-33(43)44-20-23-11-6-3-7-12-23/h2-7,9-12,14-15,17,19,26-27H,8,13,16,18,20H2,1H3,(H,37,41)(H,38,42)(H,39,43)(H4,34,35,36)
InChIKey ZZGDDBWFXDMARY-UHFFFAOYSA-N
Other name(s) Z-Phe-Arg 7-amido-4-methylcoumarin hydrochloride ; Z-FR-AMC ; Cathepsin L substrate ; AC1NNMUX ; C9521_SIGMA
________________________________________________________________________________________________
MW|612.67
Formula|C33H36N6O6
CAS_number|
PubChem|5047642
UniChem|ZZGDDBWFXDMARY-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | Z-Phe-Arg-AMC ligand of proteins in family: S9N_PREPL_Peptidase_S9

References:
Search PubMed for references concerning: Z-Phe-Arg-AMC
    Title: Crystal structure of Leishmania major oligopeptidase B gives insight into the enzymatic properties of a trypanosomatid virulence factor
    McLuskey K, Paterson NG, Bland ND, Isaacs NW, Mottram JC
    Ref: Journal of Biological Chemistry, 285:39249, 2010 : PubMed