mitoDPP-2
General
Type : Fluorescent Probe || Piperazine || Benzofuran || Xanthene
Chemical_Nomenclature : [3-[4-[6'-[methyl-[(2R)-1-(methylamino)-3-octanoylsulfanyl-1-oxopropan-2-yl]carbamoyl]oxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl]piperazin-1-yl]-3-oxopropyl]-triphenylphosphanium
Canonical SMILES : [P+](CCC(N1CCN(CC1)C2=CC3=C(C=C2)C5(C4=C(O3)C=C(C=C4)OC(=O)N([C@H](C(=O)NC)CSC(=O)CCCCCCC)C)C6=C(C(O5)=O)C=CC=C6)=O)(C7=CC=CC=C7)(C8=CC=CC=C8)C9=CC=CC=C9.[F-] || CCCCCCCC(=O)SCC(C(=O)NC)N(C)C(=O)OC1=CC2=C(C=C1)C3(C4=C(O2)C=C(C=C4)N5CCN(CC5)C(=O)CC[P+](C6=CC=CC=C6)(C7=CC=CC=C7)C8=CC=CC=C8)C9=CC=CC=C9C(=O)O3
InChI : InChI=1S\/C59H61N4O8PS.FH\/c1-4-5-6-7-17-28-55(65)73-41-51(56(66)60-2)61(3)58(68)69-43-30-32-50-53(40-43)70-52-39-42(29-31-49(52)59(50)48-27-19-18-26-47(48)57(67)71-59)62-34-36-63(37-35-62)54(64)33-38-72(44-20-11-8-12-21-44,45-22-13-9-14-23-45)46-24-15-10-16-25-46\;\/h8-16,18-27,29-32,39-40,51H,4-7,17,28,33-38,41H2,1-3H3\;1H\/t51-,59?\;\/m0.\/s1 || InChI=1S\/C59H61N4O8PS\/c1-4-5-6-7-17-28-55(65)73-41-51(56(66)60-2)61(3)58(68)69-43-30-32-50-53(40-43)70-52-39-42(29-31-49(52)59(50)48-27-19-18-26-47(48)57(67)71-59)62-34-36-63(37-35-62)54(64)33-38-72(44-20-11-8-12-21-44,45-22-13-9-14-23-45)46-24-15-10-16-25-46\/h8-16,18-27,29-32,39-40,51H,4-7,17,28,33-38,41H2,1-3H3\/p+1\/t51-,59?\/m0\/s1
InChIKey : JGCKOSKUFLQGEB-PZXRBRNOSA-N || CJVHXLDTLYVANM-HLYGUMIZSA-O
Other name(s) :
MW : 1037.19
Formula : C59H62FN4O8PS
CAS_number :
PubChem :
UniChem :
Iuphar :
Target
Families : ABHD10
References (3)
| Title : ABHD10 is an S-depalmitoylase affecting redox homeostasis through peroxiredoxin-5 - Cao_2019_Nat.Chem.Biol_15_1232 |
| Author(s) : Cao Y , Qiu T , Kathayat RS , Azizi SA , Thorne AK , Ahn D , Fukata Y , Fukata M , Rice PA , Dickinson BC |
| Ref : Nat Chemical Biology , 15 :1232 , 2019 |
| Abstract : Cao_2019_Nat.Chem.Biol_15_1232 |
| ESTHER : Cao_2019_Nat.Chem.Biol_15_1232 |
| PubMedSearch : Cao_2019_Nat.Chem.Biol_15_1232 |
| PubMedID: 31740833 |
| Gene_locus related to this paper: human-ABHD10 , mouse-abhda |
| Title : Activity-Based Sensing of S-Depalmitoylases: Chemical Technologies and Biological Discovery - Azizi_2019_Acc.Chem.Res_52_3029 |
| Author(s) : Azizi SA , Kathayat RS , Dickinson BC |
| Ref : Acc Chem Res , 52 :3029 , 2019 |
| Abstract : Azizi_2019_Acc.Chem.Res_52_3029 |
| ESTHER : Azizi_2019_Acc.Chem.Res_52_3029 |
| PubMedSearch : Azizi_2019_Acc.Chem.Res_52_3029 |
| PubMedID: 31577124 |
| Title : Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes - Kathayat_2018_Nat.Commun_9_334 |
| Author(s) : Kathayat RS , Cao Y , Elvira PD , Sandoz PA , Zaballa ME , Springer MZ , Drake LE , Macleod KF , van der Goot FG , Dickinson BC |
| Ref : Nat Commun , 9 :334 , 2018 |
| Abstract : Kathayat_2018_Nat.Commun_9_334 |
| ESTHER : Kathayat_2018_Nat.Commun_9_334 |
| PubMedSearch : Kathayat_2018_Nat.Commun_9_334 |
| PubMedID: 29362370 |
| Gene_locus related to this paper: human-LYPLA1 |