Torpedo_number

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Torpedo_number Report for: 231

human-ACHE
MutationKin.TypeEvaluation systemEffectReference
G234A sdmPROSS algorithmExpression in E ColiGoldenzweig_2016_Mol.Cell_63_337

ratno-ACHE
MutationKin.TypeEvaluation systemEffectReference
G234C sdmInactivation by sulfydrylIncreased thermal inactivationMorel_1999_Mol.Pharmacol_55_982
G234C/
L289A
 sdmPeripheral Anionic SiteIncreased thermal inactivation Increased reactivity of C234Morel_1999_Mol.Pharmacol_55_982

torma-ACHE
MutationKin.TypeEvaluation systemEffectReference
C231A sdmInactivation by sulfydrylNo inactivation by sulfydrylMorel_1999_Mol.Pharmacol_55_982
C231S sdmInactivation by sulfydrylNo inactivation by sulfydrylMorel_1999_Mol.Pharmacol_55_982
C231S sdmBack door hypothesisNo effect of mutationFaerman_1996_FEBS.Lett_386_65
V431C/
C231S
 sdmBack door hypothesisFaerman_1996_FEBS.Lett_386_65
G80C/
C231S
 sdmBack door hypothesisFaerman_1996_FEBS.Lett_386_65
G80C/
C231S/
V431C
 sdmBack door hypothesisFaerman_1996_FEBS.Lett_386_65
V129R/
C231S
 sdmBack door hypothesisNo effect of mutationFaerman_1996_FEBS.Lett_386_65
V129K/
C231S
 sdmBack door hypothesisNo effect of mutationFaerman_1996_FEBS.Lett_386_65
C231S/
L282A
 sdmPeripheral Anionic SiteIncreased thermal inactivation Increased reactivity of C231Morel_1999_Mol.Pharmacol_55_982
C231S/
N280Q/
L282S
 sdmPeripheral Anionic SiteNo increased thermal inactivation as L282mutants No increased reactivity of C231Morel_1999_Mol.Pharmacol_55_982

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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