ESTHER
Database
Home
Search
Text search
aql query
In Class
Query Builder
Preformed queries
Species
Structures
Mutations
Interactants
Diseases
Genes
Insecticides
Other
Full List
Queries for insecticide resistance
AQL exemples
Tools
Blast
HMMER
Clustal
Psiblast
Intra
Families
Overall Table
Tree Table &
Old Table
Tree Table
Old Table
Explore genes with AQL
Explore species with AQL
All figures of families
Biological
data
Structures
Table
Explore structure with AQL
Mutations
Mutation Viewer
Mutalign
Mutalign 2
Mutalign for insecticide resistance
Queries for insecticide resistance
Explore mutation with AQL
Interactants
Substrates
Inhibitors
Reactivators
Kinetic comparison tool
Inhibitor types
Substrate types
Reactivator types
Explore interactants with AQL
Diseases
Table
Explore disease with AQL
Basics on AChE
Kinetics notes
Gene structures
Molecular forms
AChE Family
Human AChE
ESTHER definition
What is up?
Likid
DB Explorer
Meetings
Suplementary Data
Latest modifications
Bibliography (all years)
Acknowledgments
& disclaimer
Torpedo_number
Kinetic parameters
Tree Display
AceDB Schema
XML Display
Feedback
Torpedo_number Report for: 365
9hyme-e2fz90
Mutation
Kin.
Type
Evaluation system
Effect
Reference
K424R
nat
OP-resistance
One or any of three mutations could give resistance
Zhuang_2014_Mol.Biol.Rep_41_7525
mouse-ACHE
Mutation
Kin.
Type
Evaluation system
Effect
Reference
D372N
sdm
Electrostatic
electrostatic influence reduced, influences FAS2 inhibition and its ionic strength dependance
Radic_1997_J.Biol.Chem_272_23265
E84Q/
E91Q/
D280V/
D283N/
D372N
sdm
Electrostatic
electrostatic influence reduced, influences FAS2 inhibition and its ionic strength dependance
Radic_1997_J.Biol.Chem_272_23265
E84Q/
E91Q/
D280V/
D283N/
E292Q/
D372N
sdm
Electrostatic
electrostatic influence reduced, influences FAS2 inhibition and its ionic strength dependance
Radic_1997_J.Biol.Chem_272_23265
Send your questions or comments to :
Mail to:
Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite:
Lenfant 2013 Nucleic.Acids.Res.
or
Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page
and
ACEDB Home Page
AcePerl Lincoln Stein Home Page
webmaster
Acknowledgements and disclaimer