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Mutation Report for: A201S_pluxy-ACHE1

Name Class
A201S_pluxy-ACHE1Gene_locuspluxy-ACHE1
Torpedo_number201
AA_ChangeA201S
Mode_of_mutationNatural mutant
ModificationOP-resistance
SummaryOP-resistance; G227A A201S A441G (G324A,A298S,A324G) found together in resistant strains but G227A likely to be important;Baek_2005_Pestic.Biochem.Physiol_81_164
OP-resistance; D131G A201S A441G (D229G,,A298S,A324G) found together in resistant strains but G227A likely to be important;Lee_2007_Biochem.Biophys.Res.Commun_353_591
OP-resistance; G227A A201S (G324A,A298S) found together in resistant strains but A201S likely to be important;Kim_2012_J.Asia.Pac.Entomol_15_401
OP-resistance; A298S and G324A mutations showed no correlation with levels of resistance to acephate;Sonoda_2014_Insect.Biochem.Mol.Biol_48_83
Paper (9)
NewsMAY-03-2005
Commentp.Ala201Ser A298S in the Plutella xylostella (L.) ACHE1. A highly resistant strain has the two mutations, a low resistant strain has only G227A (G324A) Kim et al 2012. G227A(G324A) also found in drosophila and musca domestica -ACHE (ace2 othologues of pluxy-ACHE and not pluxy-ACHE1) is likely to give resistance to OP, A298S_pluxy-ACHE1

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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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