p.Ala201Ser A298S in the Plutella xylostella (L.) ACHE1. A highly resistant strain has the two mutations, a low resistant strain has only G227A (G324A) Kim et al 2012. G227A(G324A) also found in drosophila and musca domestica -ACHE (ace2 othologues of pluxy-ACHE and not pluxy-ACHE1) is likely to give resistance to OP, A298S_pluxy-ACHE1