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Family Report for: Acidic_Lipase

Name Class
Acidic_LipaseRank2
FamilyAbhydrolase_6
Gene_locus (672)
Gene_locus_Frgt (83)
BlockX
PrositePS00120
PdocPDOC00110
Paper (20)
Structure1HLG
1K8Q
6V7N
EC_number3.1.1.3
InterproIPR039097 Gastric triacylglycerol lipase
IPR025483 Lipase, eukaryotic Lipase_euk
IPR000734 Lipase
IPR006693 AB-hydrolase-associated lipase region
CommentThis entry represents a family of eukaryotic lipases, including gastric triacylglycerol lipase (LIPF) lysosomal acid lipase (LIPA) and LIPJ, LIPK, LIPM, LIPN. Mutations in LIPA cause Wolman disease, Cholesterol Ester Storage Disease, CESD and mutation in LIPN causes Late-Onset Form of Autosomal-Recessive Congenital Ichthyosis
PfamPF04083 Abhydro_lipase
PIRSFPIRSF000862 lipase, eukaryotic type
PrintsPR00821
Inhibitor (15)
Substrate (38)

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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