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News Report for: August-10-2022

Name Class
August-10-2022Paper (8)
Structure (12)
DateAugust 10, 2022
Comment Structure of a promiscuous thioesterase domain responsible for branching acylation in polyketide biosynthesis is published by Fraley et al. and is availble (7R0X) Molecular and biochemical differences of the tandem and cold-adapted PET hydrolases Ple628 and Ple629, isolated from a marine microbial consortium are published by Meyer-Cifuentes et al. and structures will be available soon (7VMD, 7VPA). An accompagnying paper Li et al. disclose also a structure available soon (7VPB) Identification and characterization of two novel compounds: heterozygous variants of Lipoprotein Lipase in two pedigrees with type I hyperlipoproteinemia are published by Wang et al. Novel copy number variation of COLQ gene in a Moroccan patient with congenital myasthenic syndrome is published by El Kadiri et al. A highly sensitive and selective enzyme activated fluorescent probe for in vivo profiling of carboxylesterase 2 is published by Liu et al. Identification of cell wall synthesis inhibitors active against Mycobacterium tuberculosis by competitive activity-based protein profiling is published by Li et al. Multiple substrate binding mode-guided engineering of a thermophilic PET hydrolase is published by Pfaff et al. and structures are or will be available soon (7CUV, 7W69, 7W6C, 7W6O, 7W6Q, 7W66, 7E30, 7E31)

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