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Family Report for: Avian-virus_vlip

Name Class
Avian-virus_vlipRank1
Gene_locus (7)
BlockL
PaperKamil_2005_J.Virol_79_6984
InterproIPR000734 Lipase
CommentThis family has been recognized as alpha/beta hydrolase by Kamil et al. Previously associated with Lipoprotein_lipase family but is also close to phospholipase. vLIP may not serve as a traditional lipase enzyme, but the serine nucleophile position is essential in vivo for the viral functions of vLIP. Could be example of repurposing alpha/beta hydrolase fold toward a nonenzymatic role, possibly in lipid bonding
PfamPF00151 Lipase
IPR013818 Lipase
NewsJUNE-05-2005

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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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