Inhibitor Report for: Bis5-tacrine
| Bis5-tacrine | Type | Derivative of Tacrine |
|---|
| | Acridine |
| | Alkyl linked bis-ligand |
| Other_Name (6) |
| Chemical_Nomenclature | N,N'-bis(1,2,3,4-tetrahydroacridin-9-yl)pentane-1,5-diamine |
| Formula | C31H36N4 |
| MW | 464.64 |
|  |
| Paper | Rydberg_2006_J.Med.Chem_49_5491 |
| Structure | 2CMF |
| Comment | rat brain AChE IC50 (nM) 28+/-5; rat serum BuChE IC50(nM) 329+/-21 |
| Gene_locus | torca-ACHE |
| CID | 9549197 |
| Family | ACHE |
| InChIKey | NECDJQNRWSICKG-UHFFFAOYSA-N |
| CanonicalSMILES | C1CCC2=NC3=CC=CC=C3C(=C2C1)NCCCCCNC4=C5CCCCC5=NC6=CC=CC=C64 |
| InChI | InChI=1S/C31H36N4/c1(10-20-32-30-22-12-2-6-16-26(22)34-27-17-7-3-13-23(27)30)11-21-33-31-24-14-4-8-18-28(24)35-29-19-9-5-15-25(29)31/h2,4,6,8,12,14,16,18H,1,3,5,7,9-11,13,15,17,19-21H2,(H,32,34)(H,33,35) |
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