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Inhibitor Report for: Carbachol

Name Class
CarbacholType (5)
Other_NameCarbamylcholine
Carbamoylcholine
Carbastat
Carbacholin
Carbacholine
Carbacolina
Carbamiotin
Carbocholin
Carbocholine
Carbochol
Carcholin
Miostat
Carbacholinum
Karbachol
2-[(Aminocarbonyl)oxy]-N,N,N-trimethylethanaminium chloride
(2-hydroxyethyl)trimethylammonium chloride carbamate
2-carbamoyloxyethyl-trimethyl-ammonium
Chemical_Nomenclature2-carbamoyloxyethyl(trimethyl)azanium;chloride
FormulaC6H15N2O2
CAS_number51-83-2
MW147.196
PaperAuletta_2010_Chem.Biol.Interact_187_135
Rosenberry_2008_Biochemistry_47_13056
Rosenberry_2008_Chem.Biol.Interact_175_235
CommentCarbachol is a synthetic choline ester and a positively charged quaternary ammonium compound. Carbachol is a parasympathomimetic that mimics the effect of acetylcholine on both the muscarinic and nicotinic receptors. This drug is administered ocularly to induce miosis to reduce intraocular pressure in the treatment of glaucoma. Carbachol is also used to stimulate micturition by contraction of detrusor muscle. This drug may cause hypotension, bradycardia, nausea, vomiting, bronchospasm, and abdominal cramps. As a carbamate it is a slowly hydrolyzed substrate of acetylcholinesterase
CID5831
2551
FamilyACHE
BCHE
InChIKeyAIXAANGOTKPUOY-UHFFFAOYSA-N
CanonicalSMILESC[N+](C)(C)CCOC(=O)N.[Cl-]
InChIInChI=1S/C6H14N2O2.ClH/c1-8(2,3)4-5-10-6(7)9;/h4-5H2,1-3H3,(H-,7,9);1H
WikipediaCarbachol

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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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