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Substrate Report for: Carbachol

Name Class
CarbacholType (6)
Other_Name (13)
Chemical_Nomenclature2-[(Aminocarbonyl)oxy]-N,N,N-trimethylethanaminium chloride; (2-hydroxyethyl)trimethylammonium chloride carbamate ; 2-carbamoyloxyethyl-trimethyl-ammonium
FormulaC6H15N2O2
CAS_number51-83-2
MW147.196
PaperAuletta_2010_Chem.Biol.Interact_187_135
Rosenberry_2008_Biochemistry_47_13056
Rosenberry_2008_Chem.Biol.Interact_175_235
CommentParasympathomimetic, Cholinergic receptor agonist, as a carbamate it is a slowly hydrolyzed substrate of acetylcholinesterase. This drug is administered ocularly to induce miosis to reduce intraocular pressure in the treatment of glaucoma. Carbachol is also used to stimulate micturition by contraction of detrusor muscle. This drug may cause hypotension, bradycardia, nausea, vomiting, bronchospasm, and abdominal cramps.
CID5831
FamilyACHE
InChIKeyAIXAANGOTKPUOY-UHFFFAOYSA-N
CanonicalSMILESC[N+](C)(C)CCOC(=O)N.[Cl-]
InChIInChI=1S/C6H14N2O2.ClH/c1-8(2,3)4-5-10-6(7)9;/h4-5H2,1-3H3,(H-,7,9);1H
IupharLig298
WikipediaCarbachol

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