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Family Report for: Carboxymethylbutenolide_lactonase

Name Class
Carboxymethylbutenolide_lactonaseRank2
FamilyAbhydrolase_6
Alternative_names (7)
Gene_locus (721)
Gene_locus_Frgtross1-a5uys9
BlockX
MELDBTECl_3
TECl_7
Arpigny_JaegerFamily_V.2
Paper (6)
Structure2XUA
3OM8
EC_number3.1.1.24
InterproIPR000073 Alpha/beta hydrolase fold-1
IPR026968 3-oxoadipate enol-lactonase 1/2
CommentIn some instance 3-oxoadipate enol-lactonase is fused to 4-carboxymucolactone- decarboxylase, which acts on the same pathway but this enzyme belongs to CMD IPR003779 PF02627 and is not related to alpha/beta hydrolase see Eulberg et al. 1998, see Schlomann et al. 1994 fo a review on the pathway. For bacterial enzymes, this family corresponds to family V.2 of the classification of Arpigny and Jaeger 1999
PfamPF12697 Abhydrolase_6
PIRSFPIRSF000875 3-oxoadipate enol-lactonase
InhibitorLevulinic-acid
Substrate5-Methylfuran-2(3H)-one
3-Oxoadipate-enol-lactone

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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