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Mutation Report for: D340H_human-BCHE

Name Class
D340H_human-BCHEGene_locushuman-BCHE
Torpedo_number342
AA_ChangeD340H
Mode_of_mutationSite directed mutagenesis
ModificationOP-resistance
SummaryOP-resistance;increased resistance to nerve agent retained robust intrinsic catalytic efficiency;Dwyer_2014_Biochemistry_53_4476
PaperDwyer_2014_Biochemistry_53_4476
NewsJUNE-11-2014
Commentp.D340H Asp340His (p.D368H Asp368His in primary sequence with 28 amino-acids signal peptide) OP-resistance;increased resistance to nerve agent retained robust intrinsic catalytic efficiency

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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