Inhibitor Report for: DA-12166
| DA-12166 | Type (2) |
|---|
| Other_Name | 8O3 |
| Chemical_Nomenclature | (R)-4-(3-amino-4-(2,4,5-trifluorophenyl)butanoyl)piperazin-2-one |
| Formula | C14H16F3N3O2 |
| MW | 315.29 |
|  |
| Paper | Lee_2017_Biochem.Biophys.Res.Commun_494_452 |
| Structure | 5Y7H |
| Comment | Evogliptin and DA-12228 are derivatives of DA-12166 DPP4 IC50 18.7 nM |
| Gene_locus | human-DPP4 |
| CID | 137551959 |
| Family | DPP4N_Peptidase_S9 |
| InChIKey | SLQOQKROMQOJLJ-SECBINFHSA-N |
| CanonicalSMILES | N[C@@H](CC(=O)N1CCNC(=O)C1)Cc1cc(F)c(F)cc1F |
| InChI | InChI=1S/C14H16F3N3O2/c15-10-6-12(17)11(16)4-8(10)3-9(18)5-14(22)20-2-1-19-13(21)7-20/h4,6,9H,1-3,5,7,18H2,(H,19,21)/t9-/m1/s1 |
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