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Inhibitor Report for: DH376
Name
Class
DH376
Type
Piperidine
Triazol
Urea derivative
Other_Name (6)
Chemical_Nomenclature
[(2R,5R)-2-benzyl-5-prop-2-ynoxypiperidin-1-yl]-[4-[bis(4-fluorophenyl)-hydroxymethyl]triazol-2-yl]methanone
Formula
C31H28F2N4O3
CAS_number
1848233-57-7
MW
542.6
Paper
Berger_2023_Front.Endocrinol.(Lausanne)_14_1092024
Deng_2017_J.Med.Chem_60_428
Ogasawara_2016_Proc.Natl.Acad.Sci.U.S.A_113_26
van Rooden_2018_Nat.Protoc_13_752
Gene_locus
human-DAGLA
human-DAGLB
CID
129188688
Family
Lipase_3
InChIKey
GVLOFRPVRYAFKI-VSGBNLITSA-N
CanonicalSMILES
C#CCOC1CCC(N(C1)C(=O)N2N=CC(=N2)C(C3=CC=C(C=C3)F)(C4=CC=C(C=C4)F)O)CC5=CC=CC=C5
InChI
InChI=1S/C31H28F2N4O3/c1-2-18-40-28-17-16-27(19-22-6-4-3-5-7-22)36(21-28)30(38)37-34-20-29(35-37)31(39,23-8-12-25(32)13-9-23)24-10-14-26(33)15-11-24/h1,3-15,20,27-28,39H,16-19,21H2/t27-,28-/m1/s1
Send your questions or comments to :
Mail to:
Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite:
Lenfant 2013 Nucleic.Acids.Res.
or
Marchot Chatonnet 2012 Prot.Pept Lett.
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