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Inhibitor Report for: Desoxypeganine
Name
Class
Desoxypeganine
Type
Not A/B H target
Alkaloid
Natural
Quinazoline
Other_Name (7)
Chemical_Nomenclature
1,2,3,9-tetrahydropyrrolo[2,1-b]quinazoline
Formula
C11H12N2HCl 2H2O
CAS_number
61939-05-7
459-59-0
MW
245
Paper
Lockhart_2001_Naunyn.Schmiedebergs.Arch.Pharmacol_363_429
Tuliaganov_1986_Farmakol.Toksikol_49_37
Comment
Alkaloid from plants of the Zygophyllaceae family Inhibits both cholinesterases and monoamine oxydases.Inhibits butyrylcholinesterase more strongly than acetylcholinesterase. Desoxypeganine hydrochloride crosses easily the blood-brain barrier.
CID
442894
Family
ACHE
BCHE
InChIKey
WUFQLZTXIWKION-UHFFFAOYSA-N
CanonicalSMILES
C1CC2=NC3=CC=CC=C3CN2C1
InChI
InChI=1S/C11H12N2/c1-2-5-10-9(4-1)8-13-7-3-6-11(13)12-10/h1-2,4-5H,3,6-8H2
Send your questions or comments to :
Mail to:
Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite:
Lenfant 2013 Nucleic.Acids.Res.
or
Marchot Chatonnet 2012 Prot.Pept Lett.
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